Is the vaccine effective in preventing chickenpox all the time?

No vaccine is 100% effective in preventing disease. For chickenpox vaccine, about 9 out of 10 people who are vaccinated with two doses are completely protected from chickenpox infection and almost 100% from severe disease. If a vaccinated person does get chickenpox, it is usually a very mild case with fewer skin lesions (usually less than 50) lasting only a few days, no fever or a low fever, and few other symptoms. This form of chickenpox is also called breakthrough disease, and is more common in those who only received one dose of vaccine.

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